Optogenetic manipulation of cyclic guanosine monophosphate to probe phosphodiesterase activities in megakaryocytes

Cyclic guanosine monophosphate (cGMP) signalling plays a fundamental role in many Military Spacecraft Model Kit cell types, including platelets.cGMP has been implicated in platelet formation, but mechanistic detail about its spatio-temporal regulation in megakaryocytes (MKs) is lacking.Optogenetics is a technique which allows spatio-temporal manipu

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The impact of infrastructural change and regulation on entrepreneurial competitiveness in the South African telecommunications sector

The fast pace of technological advancements is regarded as one of Arthritis Gloves the global drivers of change.In the telecommunications sector in South Africa, these technological advancements as well as sector transformation pose competitiveness challenges to entrepreneurs.This paper reports an empirical study performed to contribute to the prom

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Fulminant hepatitis B: A case report

Introduction: Fulminant hepatitis is a severe acute liver disease.It occurs due to massive Toy Ponies necrosis of hepatocytes.The disease progresses to lethal outcome within a few days.The most common causes of this disease are toxic substances, autoimmune and viral hepatitis.The aim of the study was to present a lethal case of fulminant hepatitis

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